“Some battles are not seen on the skin, but felt in the soul.”

Introduction: When Pleasure Turns into Pain due to Post Orgasmic Illness Syndrome (POIS)

Are you or someone you know feeling sick, mentally foggy, or even depressed after sexual activity, ejaculation, seminal discharge or orgasm? If yes, you are not alone. You may be experiencing a rare but real condition called Post Orgasmic Illness Syndrome (POIS). Although not well known, it is a real and distressing condition that can deeply impact a person’s quality of life, relationships, and self-esteem.

As Dr. Hitesh Shah, the best sexologist in Mumbai, and the innovator of the copyright-registered ‘Integrated Sexology(R)’ approach, I have successfully helped many men and women suffering silently from POIS.

🌐 Consult in person or online at: 301, Sanjar Enclave, S.V. Road, Kandivali West, Mumbai 400067
📱 Call/WhatsApp for appointments: +91 9819035111

⚠️ Caution: Do NOT self-medicate. Always consult an expert.

What is POIS?

Post Orgasmic Illness Syndrome (P.O.I.S.) is a rare condition where an individual—most commonly a man—experiences physical, emotional, cognitive, and flu-like symptoms after ejaculation or orgasm. These symptoms can last from a few hours to up to a week or more.

Common Symptoms:

Mental fogginess
Fatigue and weakness
Irritability or depression
Muscle pain and body aches
Itchy or watery eyes
Low-grade fever
Diarrhoea or abdominal cramps
Headache
Burning sensation in the eyes or face

These symptoms usually begin within 30 minutes to 1 hour after orgasm and can disrupt both sexual and daily life.

Prevalence, Age & Sex Distribution of P.O.I.S.

More common in males but may occur in females as well.
Usually seen in ages 20 to 45, though younger and older men are not exempt.
Often underdiagnosed due to lack of awareness among patients and doctors.

A 2018 study in Sexual Medicine Reviews estimated less than 1% prevalence, though actual numbers may be much higher due to non-reporting.

Bio-Physio-Pathology OF P.O.I.S.: What Goes Wrong?

The exact cause remains unclear, but leading hypotheses include:

Brain Chemistry:

Dopamine exhaustion: Dopamine spikes during orgasm, followed by a sudden drop, can lead to fatigue and emotional dullness.
Endorphin imbalance: Natural opiates crash post-orgasm, leading to flu-like symptoms.
Immune response: Autoimmune/allergic reaction to one’s own semen (Type I or IV hypersensitivity).

Other Theories:

Neuroinflammation
Proinflammatory cytokines release
Autonomic nervous system imbalance

POIS is considered a diagnosis of exclusion, meaning other conditions must first be ruled out.

What Else to Rule Out?

Before confirming POIS, rule out:

Depression or anxiety disorders
Chronic fatigue syndrome (CFS)
Sexual performance anxiety
Post-coital dysphoria
Hormonal imbalances (Testosterone, Thyroid)
Adrenal fatigue
Food allergies
Infections (UTI, prostatitis)

Diagnosis: Listen to the Story

There is no lab test for POIS. It is diagnosed based on:

Detailed case history
Symptom pattern (timing & duration after orgasm)
Elimination of other medical conditions
Patient diary or symptom log

🧠 Integrated Sexology(R) insists on listening deeply, observing patterns, and correlating emotional, sexual, psychological, and physical aspects.

Integrated Sexology® Treatment: Natural, Multidisciplinary, Long-Lasting

At our clinic, we use an individualised and holistic approach integrating:

✅ Classical Homeopathy

✅ Modern Medical Evaluation

✅ Behavioural Sex Therapy

✅ Ayurvedic Detox & Rejuvenation

✅ Stress & Lifestyle Management

✅ Couple & Personal Counselling

Our goal? Long-term, side-effect-free, dependency-free solutions.

Homeopathic Remedies: Personalized Healing from Within

🎯 Key Remedies & Indications:

Selenium 200 – For weakness after sex, trembling, memory issues, emotional dullness.
Kali Phos 6x – For nervous exhaustion, mental fatigue, and irritability.
Staphysagria 200 – For suppressed emotions, performance anxiety, guilt.
Phosphoric Acid 30 – For brain fog, apathy, and mental dullness.
Lycopodium 1M – For fear of failure, premature ejaculation, bloating post-orgasm.
Nux Vomica 200 – For irritability, fatigue, overstimulation with poor digestion.
Agnus Castus Q – For complete sexual exhaustion with mental despair.

Each remedy is chosen based on complete mind-body analysis, not just symptoms.

Real-Life Stories of Healing: 7 Inspiring Case Studies

Case 1: Rahul, 28, IT Professional

Symptoms: Brain fog, guilt, anxiety, flu-like fatigue post sex
Remedy: Staphysagria 200
Outcome: Relief in 3 months. Restarted healthy intimacy with fiancée 💕

Case 2: Nilesh, 35, Banker

Symptoms: Sneezing, weakness, muscle pain post masturbation
Remedy: Selenium 200
Outcome: Dramatic recovery. Became an advocate for sexual wellness.

Case 3: Zoya, 31, Newlywed Woman

Symptoms: Body ache, tearfulness post-orgasm
Remedy: Phosphoric Acid 30
Outcome: Emotional healing + sexual confidence bloomed 🌹

Case 4: Ashwin, 22, Engineering Student

Symptoms: Anger, sleep issues, exhaustion
Remedy: Nux Vomica 200 + Behavioural Counselling
Outcome: Balanced mood, improved academics, zero relapses

Case 5: Pratik, 42, Entrepreneur

Symptoms: Bloating, low energy, irritability
Remedy: Lycopodium 1M + Ayurveda Support
Outcome: Rejuvenated. Wife noticed the difference! 😄

Case 6: Maya, 26, Teacher

Symptoms: Depression, shame, headache post intimacy
Remedy: Kali Phos 6x + Sex Therapy
Outcome: Newfound joy in intimacy. Marriage strengthened ❤️

Case 7: Vishal, 38, Lawyer

Symptoms: Memory lapses, breathlessness, low libido
Remedy: Agnus Castus Q + Lifestyle Coaching
Outcome: Regained clarity, built stamina, regained spark 🔥

Final Thoughts: There is Hope, There is Healing

POIS may feel like a punishment for pleasure—but it doesn’t have to be that way. With the Integrated Sexology® approach, we treat the person, not just the problem.

🕊️ Your body is trying to talk to you. Listen with care. Heal with guidance.

✨ “Sexual wellness is not just about sex. It’s about your whole being.” – Dr. Hitesh Shah

🔗 External Links for Further Reading:

🧠 Internal Link: Consult Dr. Hitesh Shah – Book Your Appointment

For expert, personalized care:
🏥 Dr. Hitesh Shah, 301, Sanjar Enclave, S.V. Road, Kandivali West, Mumbai – 400067
📞 WhatsApp/Call: 9819035111
🌐 www.sexologist.info

💬 Comment below or message us for more information or to share your experience. Let’s break the silence around POIS!